max_allowed_packet sets an upper limit on the size of any single message between the MySQL server and clients, including replication slaves. If you are replicating large column values (such as might be found in TEXT or BLOB columns) and max_allowed_packet is too small on the master, the master fails with an error, and the slave shuts down the I/O thread. If max_allowed_packet is too small on the slave, this also causes the slave to stop the I/O thread.

Prior to MySQL 5.1.40, Last_IO_Error and Last_IO_Errno in the output of SHOW SLAVE STATUS were not set in the event that replication failed due to exceeding max_allowed_packet (Bug#42914).

Row-based replication currently sends all columns and column values for updated rows from the master to the slave, including values of columns that were not actually changed by the update. This means that, when you are replicating large column values using row-based replication, you must take care to set max_allowed_packet large enough to accommodate the largest row in any table to be replicated, even if you are replicating updates only, or you are inserting only relatively small values.